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Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors
Nicotinic acetylcholine receptors (nAChR) are pentameric ligand-gated ion channels composed of subunits that consist of an extracellular domain that carries the ligand-binding site and a distinct ion-pore domain. Signal transduction results from the allosteric coupling between the two domains: the d...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1629088/ https://ncbi.nlm.nih.gov/pubmed/17077146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607477103 |
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