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A QUANTITATIVE MODEL OF ERROR ACCUMULATION DURING PCR AMPLIFICATION

The amplification of target DNA by the polymerase chain reaction (PCR) produces copies which may contain errors. Two sources of errors are associated with the PCR process: (1) editing errors that occur during DNA polymerase-catalyzed enzymatic copying and (2) errors due to DNA thermal damage. In thi...

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Hlavní autoři: Pienaar, E, Theron, M, Nelson, M, Viljoen, HJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544370/
https://ncbi.nlm.nih.gov/pubmed/16412692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2005.11.002
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