Target enrichment using parallel nanoliter quantitative PCR amplification

BACKGROUND: Next generation targeted resequencing is replacing Sanger sequencing at high pace in routine genetic diagnosis. The need for well validated, high quality enrichment platforms to complement the bench-top next generation sequencing devices is high. RESULTS: We used the WaferGen Smartchip p...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: De Wilde, Bram, Lefever, Steve, Dong, Wes, Dunne, Jude, Husain, Syed, Derveaux, Stefaan, Hellemans, Jan, Vandesompele, Jo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234423/
https://ncbi.nlm.nih.gov/pubmed/24612714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-184
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