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A QUANTITATIVE MODEL OF ERROR ACCUMULATION DURING PCR AMPLIFICATION
The amplification of target DNA by the polymerase chain reaction (PCR) produces copies which may contain errors. Two sources of errors are associated with the PCR process: (1) editing errors that occur during DNA polymerase-catalyzed enzymatic copying and (2) errors due to DNA thermal damage. In thi...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544370/ https://ncbi.nlm.nih.gov/pubmed/16412692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2005.11.002 |
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