Φορτώνει......
Ca(2+)-Triggered Simultaneous Membrane Penetration of the Tandem C2-Domains of Synaptotagmin I
Synaptotagmin I (syt), a transmembrane protein localized to secretory vesicles, functions as a Ca(2+) sensor that facilitates SNARE-mediated membrane fusion. The cytoplasmic domain of syt harbors two C2-domains designated C2A and C2B. Upon binding Ca(2+), C2A and C2B partially penetrate into membran...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Biophysical Society
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544279/ https://ncbi.nlm.nih.gov/pubmed/16782782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080325 |
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