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Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities

Yeast prions are protein-based genetic elements that self-perpetuate changes in protein conformation and function. A protein-remodeling factor, Hsp104, controls the inheritance of several yeast prions, including those formed by Sup35 and Ure2. Perplexingly, deletion of Hsp104 eliminates Sup35 and Ur...

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Detalhes bibliográficos
Main Authors: Shorter, James, Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1540446/
https://ncbi.nlm.nih.gov/pubmed/16885031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.042
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