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Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
Two members of the AAA+ superfamily, ClpB and Hsp104, collaborate with Hsp70 and Hsp40 to rescue aggregated proteins. However, the mechanisms that elicit and underlie their protein-remodeling activities remain unclear. We report that for both Hsp104 and ClpB, mixtures of ATP and ATPγS unexpectedly u...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1793998/ https://ncbi.nlm.nih.gov/pubmed/17259993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1198 |
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