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The elusive middle domain of Hsp104 and ClpB: location and function
Hsp104 in yeast and ClpB in bacteria are homologous, hexameric AAA+ proteins and Hsp100 chaperones that function in the stress response as ring-translocases that drive protein disaggregation and reactivation. Both Hsp104 and ClpB contain a distinctive coiled-coil middle domain (MD) inserted in the f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219823/ https://ncbi.nlm.nih.gov/pubmed/21843558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.07.014 |
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