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Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions
Self-templating amyloid forms of Sup35 constitute the yeast prion [PSI(+)]. How the protein-remodelling factor, Hsp104, collaborates with other chaperones to regulate [PSI(+)] inheritance remains poorly delineated. Here, we report how the Ssa and Ssb components of the Hsp70 chaperone system directly...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572177/ https://ncbi.nlm.nih.gov/pubmed/18833196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.194 |
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