Variant‐specific and reciprocal Hsp40 functions in Hsp104‐mediated prion elimination

The amyloid‐based prions of Saccharomyces cerevisiae are heritable aggregates of misfolded proteins, passed to daughter cells following fragmentation by molecular chaperones including the J‐protein Sis1, Hsp70 and Hsp104. Overexpression of Hsp104 efficiently cures cell populations of the prion [PSI...

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Detaylı Bibliyografya
Yayımlandı:Mol Microbiol
Asıl Yazarlar: Astor, Michael T., Kamiya, Erina, Sporn, Zachary A., Berger, Scott E., Hines, Justin K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099457/
https://ncbi.nlm.nih.gov/pubmed/29633387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13966
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