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Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity

Yeast prions are heritable protein-based elements, most of which are formed of amyloid aggregates that rely on the action of molecular chaperones for transmission to progeny. Prions can form distinct amyloid structures, known as ‘strains’ in mammalian systems, that dictate both pathological progress...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Sporn, Zachary A, Hines, Justin K
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601347/
https://ncbi.nlm.nih.gov/pubmed/25738774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1020268
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