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Prion propagation by Hsp40 molecular chaperones

Molecular chaperones regulate essential steps in the propagation of yeast prions. Yeast prions possess domains enriched in glutamines and asparagines that act as templates to drive the assembly of native proteins into beta-sheet-rich, amyloid-like fibrils. Several recent studies highlight a signific...

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Bibliografiske detaljer
Main Authors: Summers, Daniel W, Douglas, Peter M, Cyr, Douglas M
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712600/
https://ncbi.nlm.nih.gov/pubmed/19535913
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