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Variant‐specific and reciprocal Hsp40 functions in Hsp104‐mediated prion elimination

The amyloid‐based prions of Saccharomyces cerevisiae are heritable aggregates of misfolded proteins, passed to daughter cells following fragmentation by molecular chaperones including the J‐protein Sis1, Hsp70 and Hsp104. Overexpression of Hsp104 efficiently cures cell populations of the prion [PSI...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Microbiol
Päätekijät: Astor, Michael T., Kamiya, Erina, Sporn, Zachary A., Berger, Scott E., Hines, Justin K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099457/
https://ncbi.nlm.nih.gov/pubmed/29633387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13966
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