Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104

Hsp104, a yeast protein-remodeling factor of the AAA+ (ATPases associated with various cellular activities) superfamily, and its homologs in bacteria and plants mediate cell recovery after severe stress by disaggregating denatured proteins through a poorly understood mechanism. Here, we present cryo...

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Detalhes bibliográficos
Main Authors: Wendler, Petra, Shorter, James, Plisson, Celia, Cashikar, Anil G., Lindquist, Susan, Saibil, Helen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2007
Assuntos:
Matters Arising
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211523/
https://ncbi.nlm.nih.gov/pubmed/18160044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.10.047
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