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Prion proteostasis: Hsp104 meets its supporting cast

Infectious amyloid forms of the release factor, Sup35, comprise the yeast prion [PSI(+)]. This protein-based unit of inheritance is an evolutionary capacitor able to release cryptic genetic variation during environmental stress and generate potentially beneficial phenotypes. Genetic data have uncove...

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Detalhes bibliográficos
Main Authors: Sweeny, Elizabeth A, Shorter, James
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658762/
https://ncbi.nlm.nih.gov/pubmed/19242125
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