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Proteomic profiling of metalloprotease activities with cocktails of active-site probes

Metalloproteases are a large, diverse class of enzymes involved in many physiological and disease processes. Metalloproteases are regulated by post-translational mechanisms that diminish the effectiveness of conventional genomic and proteomic methods for their functional characterization. Chemical p...

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Bibliografiske detaljer
Main Authors: Sieber, Stephan A, Niessen, Sherry, Hoover, Heather S, Cravatt, Benjamin F
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538544/
https://ncbi.nlm.nih.gov/pubmed/16565715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio781
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