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An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis

A significant gap exists between genetics-based investigations of polyketide synthases (PKS) and nonribosomal peptide synthetase (NRPS) biosynthetic pathways and our understanding of their regulation, interaction, and activity in living systems. To help bridge this gap, here we present an Orthogonal...

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Detalhes bibliográficos
Main Authors: Meier, Jordan L., Niessen, Sherry, Hoover, Heather S., Foley, Timothy L., Cravatt, Benjamin F., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818308/
https://ncbi.nlm.nih.gov/pubmed/19785476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9002128
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