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Activity-based probes for proteomic profiling of histone deacetylase complexes

Histone deacetylases (HDACs) are key regulators of gene expression that require assembly into larger protein complexes for activity. Efforts to understand how associated proteins modulate the function of HDACs would benefit from new technologies that evaluate HDAC activity in native biological syste...

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Detalhes bibliográficos
Main Authors: Salisbury, Cleo M., Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783107/
https://ncbi.nlm.nih.gov/pubmed/17227860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608659104
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