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Chemical proteomic probes for profiling cytochrome P450 activities and drug interactions in vivo
The cytochrome P450 (P450) superfamily metabolizes many endogenous signaling molecules and drugs. P450 enzymes are regulated by post-translational mechanisms in vivo, which hinders their functional characterization by conventional genomic or proteomic methods. Here, we describe a chemical proteomic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2044501/ https://ncbi.nlm.nih.gov/pubmed/17884636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.08.008 |
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