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A Suite of Activity-Based Probes for Human Cytochrome P450 Enzymes
Cytochrome P450 (P450) enzymes regulate a variety of endogenous signaling molecules and play central roles in the metabolism of xenobiotics and drugs. We recently showed that an aryl alkyne serves as an effective activity-based probe for profiling mouse liver microsomal P450s in vitro and in vivo. H...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737065/ https://ncbi.nlm.nih.gov/pubmed/19583257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9037609 |
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