Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450

NADPH-cytochrome P450 reductase (CPR) is the unique redox partner of microsomal cytochrome P450s (CYPs). CPR exists in a conformational equilibrium between open and closed conformations throughout its electron transfer (ET) function. Previously, we have shown that electrostatic and flexibility prope...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Campelo, Diana, Esteves, Francisco, Brito Palma, Bernardo, Costa Gomes, Bruno, Rueff, José, Lautier, Thomas, Urban, Philippe, Truan, Gilles, Kranendonk, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321550/
https://ncbi.nlm.nih.gov/pubmed/30563285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123914
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