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Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding
The activity of microsomal cytochromes P450 (CYP) is strictly dependent on the supply of electrons provided by NADPH cytochrome P450 oxidoreductase (CPR). The variant nature of the isoform-specific proximal interface of microsomal CYPs implies that the interacting interface between the two proteins...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2020-09-01
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| Серии: | International Journal of Molecular Sciences |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/1422-0067/21/18/6669 |
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