Pathogenesis of Herpes Simplex Virus Type 2 Virion Host Shutoff (vhs) Mutants
During lytic infection, the virion host shutoff (vhs) protein mediates the rapid degradation of mRNA and the shutoff of host protein synthesis. In vivo, herpes simplex virus type 1 (HSV-1) mutants lacking vhs activity are profoundly attenuated. Homologs of vhs exist in all of the neurotropic herpesv...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2054-2061.2002 |
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