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Direct localization of a β-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase

To identify the location of a domain of the β-subunit of Escherichia coli RNA polymerase (RNAP) on the three-dimensional structure, we developed a method to tag a nonessential surface of the multisubunit enzyme with a protein density easily detectable by electron microscopy and image processing. Fou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Opalka, Natacha, Mooney, Rachel A., Richter, Catherine, Severinov, Konstantin, Landick, Robert, Darst, Seth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15379/
https://ncbi.nlm.nih.gov/pubmed/10639128
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