Topology of the RNA polymerase active center probed by chimeric rifampicin-nucleotide compounds.

Spatial organization of the binding sites for the priming substrate, the template DNA, and the transcription inhibitor rifampicin (Rif) in Escherichia coli RNA polymerase (EC 2.7.7.6) was probed with chimeric compounds in which Rif is covalently attached to a ribonucleotide. The compounds bind to RN...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mustaev, A, Zaychikov, E, Severinov, K, Kashlev, M, Polyakov, A, Nikiforov, V, Goldfarb, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12036
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