Topology of the RNA polymerase active center probed by chimeric rifampicin-nucleotide compounds.

Spatial organization of the binding sites for the priming substrate, the template DNA, and the transcription inhibitor rifampicin (Rif) in Escherichia coli RNA polymerase (EC 2.7.7.6) was probed with chimeric compounds in which Rif is covalently attached to a ribonucleotide. The compounds bind to RN...

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Main Authors: Mustaev, A, Zaychikov, E, Severinov, K, Kashlev, M, Polyakov, A, Nikiforov, V, Goldfarb, A
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC45371/
https://ncbi.nlm.nih.gov/pubmed/7991580
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