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Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrate

A 16-aa insertion loop present in eubacterial methionyl-tRNA formyltransferases (MTF) is critical for specific recognition of the initiator tRNA in Escherichia coli. We have studied the interactions between this region of the E. coli enzyme and initiator methionyl-tRNA (Met-tRNA) by using two comple...

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Main Authors: Ramesh, Vaidyanathan, Mayer, Christine, Dyson, Michael R., Gite, Sadanand, RajBhandary, Uttam L.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC15318/
https://ncbi.nlm.nih.gov/pubmed/9927661
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