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Twenty-first aminoacyl-tRNA synthetase–suppressor tRNA pairs for possible use in site-specific incorporation of amino acid analogues into proteins in eukaryotes and in eubacteria

Two critical requirements for developing methods for the site-specific incorporation of amino acid analogues into proteins in vivo are (i) a suppressor tRNA that is not aminoacylated by any of the endogenous aminoacyl-tRNA synthetases (aaRSs) and (ii) an aminoacyl-tRNA synthetase that aminoacylates...

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Detalhes bibliográficos
Main Authors: Kowal, Anne K., Köhrer, Caroline, RajBhandary, Uttam L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30127/
https://ncbi.nlm.nih.gov/pubmed/11226228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031488298
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