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The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase

The crystal structure of an enzyme–substrate complex with histidyl-tRNA synthetase from Escherichia coli, ATP, and the amino acid analog histidinol is described and compared with the previously obtained enzyme–product complex with histidyl-adenylate. An active site arginine, Arg-259, unique to all h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arnez, John G., Augustine, John G., Moras, Dino, Francklyn, Christopher S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23771/
https://ncbi.nlm.nih.gov/pubmed/9207058
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