Expression of Escherichia coli Methionyl-tRNA Formyltransferase in Saccharomyces cerevisiae Leads to Formylation of the Cytoplasmic Initiator tRNA and Possibly to Initiation of Protein Synthesis with Formylmethionine

Protein synthesis in eukaryotic cytoplasm and in archaebacteria is initiated with methionine, whereas, that in eubacteria and in eukaryotic organelles, such as mitochondria and chloroplasts, is initiated with formylmethionine. In view of this clear distinction, we have investigated whether protein s...

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Hauptverfasser: Ramesh, Vaidyanathan, Köhrer, Caroline, RajBhandary, Uttam L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133937/
https://ncbi.nlm.nih.gov/pubmed/12101237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5434-5442.2002
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