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Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrate

A 16-aa insertion loop present in eubacterial methionyl-tRNA formyltransferases (MTF) is critical for specific recognition of the initiator tRNA in Escherichia coli. We have studied the interactions between this region of the E. coli enzyme and initiator methionyl-tRNA (Met-tRNA) by using two comple...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Ramesh, Vaidyanathan, Mayer, Christine, Dyson, Michael R., Gite, Sadanand, RajBhandary, Uttam L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.875
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