Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrate

A 16-aa insertion loop present in eubacterial methionyl-tRNA formyltransferases (MTF) is critical for specific recognition of the initiator tRNA in Escherichia coli. We have studied the interactions between this region of the E. coli enzyme and initiator methionyl-tRNA (Met-tRNA) by using two comple...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Ramesh, Vaidyanathan, Mayer, Christine, Dyson, Michael R., Gite, Sadanand, RajBhandary, Uttam L.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.875
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