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Selection of suppressor methionyl-tRNA synthetases: mapping the tRNA anticodon binding site.

Accurate aminoacylation of a tRNA by Escherichia coli methionyl-tRNA synthetase (MTS) is specified by the CAU anticodon. A genetic screening procedure was designed to isolate MTS mutants able to aminoacylate a methionine amber tRNA (CUA anticodon). Selected suppressor MTS enzymes all possess one or...

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Autors principals: Meinnel, T, Mechulam, Y, Le Corre, D, Panvert, M, Blanquet, S, Fayat, G
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50796/
https://ncbi.nlm.nih.gov/pubmed/1986377
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