Selection of suppressor methionyl-tRNA synthetases: mapping the tRNA anticodon binding site.

Accurate aminoacylation of a tRNA by Escherichia coli methionyl-tRNA synthetase (MTS) is specified by the CAU anticodon. A genetic screening procedure was designed to isolate MTS mutants able to aminoacylate a methionine amber tRNA (CUA anticodon). Selected suppressor MTS enzymes all possess one or...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Meinnel, T, Mechulam, Y, Le Corre, D, Panvert, M, Blanquet, S, Fayat, G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.291
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