Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog
The specific recognition of homopurine–homo pyrimidine regions in duplex DNA by triplex-forming oligonucleotides (TFOs) provides an attractive strategy for genetic manipulation. Alkylation of nucleobases with functionalized TFOs would have the potential for site-directed mutagenesis. Recently, we de...
में बचाया:
| में प्रकाशित: | Nucleic Acids Res |
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| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2003
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12626730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng031 |
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