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Triglyceride accumulation protects against fatty acid-induced lipotoxicity

Excess lipid accumulation in non-adipose tissues is associated with insulin resistance, pancreatic β-cell apoptosis and heart failure. Here, we demonstrate in cultured cells that the relative toxicity of two common dietary long chain fatty acids is related to channeling of these lipids to distinct c...

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Autors principals: Listenberger, Laura L., Han, Xianlin, Lewis, Sarah E., Cases, Sylvaine, Farese, Robert V., Ory, Daniel S., Schaffer, Jean E.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152249/
https://ncbi.nlm.nih.gov/pubmed/12629214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0630588100
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