Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Although diabetic cardiomyopathy is associated with enhanced intramyocardial triacylglycerol (TAG) levels, the role of TAG catabolizing enzymes in this process is unclear. Because the TAG hydrolase, adipose triglyceride lipase (ATGL), regulates baseline cardiac metabolism and function, we examined w...

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Main Authors: Pulinilkunnil, Thomas, Kienesberger, Petra C., Nagendran, Jeevan, Waller, Terri J., Young, Martin E., Kershaw, Erin E., Korbutt, Gregory, Haemmerle, Guenter, Zechner, Rudolf, Dyck, Jason R.B.
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://ncbi.nlm.nih.gov/pubmed/23349479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0927
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