Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Although diabetic cardiomyopathy is associated with enhanced intramyocardial triacylglycerol (TAG) levels, the role of TAG catabolizing enzymes in this process is unclear. Because the TAG hydrolase, adipose triglyceride lipase (ATGL), regulates baseline cardiac metabolism and function, we examined w...

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Bibliografiske detaljer
Main Authors: Pulinilkunnil, Thomas, Kienesberger, Petra C., Nagendran, Jeevan, Waller, Terri J., Young, Martin E., Kershaw, Erin E., Korbutt, Gregory, Haemmerle, Guenter, Zechner, Rudolf, Dyck, Jason R.B.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://ncbi.nlm.nih.gov/pubmed/23349479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0927
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