Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Although diabetic cardiomyopathy is associated with enhanced intramyocardial triacylglycerol (TAG) levels, the role of TAG catabolizing enzymes in this process is unclear. Because the TAG hydrolase, adipose triglyceride lipase (ATGL), regulates baseline cardiac metabolism and function, we examined w...

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Bibliographische Detailangaben
Hauptverfasser: Pulinilkunnil, Thomas, Kienesberger, Petra C., Nagendran, Jeevan, Waller, Terri J., Young, Martin E., Kershaw, Erin E., Korbutt, Gregory, Haemmerle, Guenter, Zechner, Rudolf, Dyck, Jason R.B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://ncbi.nlm.nih.gov/pubmed/23349479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0927
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