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Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling
Triacylglycerol accumulation in insulin target tissues is associated with insulin resistance. Paradoxically, mice with global targeted deletion of adipose triglyceride lipase (ATGL), the rate-limiting enzyme in triacylglycerol hydrolysis, display improved glucose tolerance and insulin sensitivity de...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781577/ https://ncbi.nlm.nih.gov/pubmed/19723629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047787 |
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