Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages. To investigate the relative contribution of free fatty acids (FFAs) in this process, we de...

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Hlavní autoři: Chandak, Prakash G., Radović, Branislav, Aflaki, Elma, Kolb, Dagmar, Buchebner, Marlene, Fröhlich, Eleonore, Magnes, Christoph, Sinner, Frank, Haemmerle, Guenter, Zechner, Rudolf, Tabas, Ira, Levak-Frank, Sanja, Kratky, Dagmar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888432/
https://ncbi.nlm.nih.gov/pubmed/20424161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107854
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