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Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages. To investigate the relative contribution of free fatty acids (FFAs) in this process, we de...

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Bibliographische Detailangaben
Hauptverfasser: Chandak, Prakash G., Radović, Branislav, Aflaki, Elma, Kolb, Dagmar, Buchebner, Marlene, Fröhlich, Eleonore, Magnes, Christoph, Sinner, Frank, Haemmerle, Guenter, Zechner, Rudolf, Tabas, Ira, Levak-Frank, Sanja, Kratky, Dagmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888432/
https://ncbi.nlm.nih.gov/pubmed/20424161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107854
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