Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Although diabetic cardiomyopathy is associated with enhanced intramyocardial triacylglycerol (TAG) levels, the role of TAG catabolizing enzymes in this process is unclear. Because the TAG hydrolase, adipose triglyceride lipase (ATGL), regulates baseline cardiac metabolism and function, we examined w...

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Hlavní autoři: Pulinilkunnil, Thomas, Kienesberger, Petra C., Nagendran, Jeevan, Waller, Terri J., Young, Martin E., Kershaw, Erin E., Korbutt, Gregory, Haemmerle, Guenter, Zechner, Rudolf, Dyck, Jason R.B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://ncbi.nlm.nih.gov/pubmed/23349479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0927
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