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A Critical Role for Eukaryotic Elongation Factor 1A-1 in Lipotoxic Cell Death
The deleterious consequences of fatty acid (FA) and neutral lipid accumulation in nonadipose tissues, such as the heart, contribute to the pathogenesis of type 2 diabetes. To elucidate mechanisms of FA-induced cell death, or lipotoxicity, we generated Chinese hamster ovary (CHO) cell mutants resista...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356587/ https://ncbi.nlm.nih.gov/pubmed/16319173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0742 |
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