A Critical Role for Eukaryotic Elongation Factor 1A-1 in Lipotoxic Cell Death

The deleterious consequences of fatty acid (FA) and neutral lipid accumulation in nonadipose tissues, such as the heart, contribute to the pathogenesis of type 2 diabetes. To elucidate mechanisms of FA-induced cell death, or lipotoxicity, we generated Chinese hamster ovary (CHO) cell mutants resista...

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Huvudupphovsmän: Borradaile, Nica M., Buhman, Kimberly K., Listenberger, Laura L., Magee, Carolyn J., Morimoto, Emiko T.A., Ory, Daniel S., Schaffer, Jean E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356587/
https://ncbi.nlm.nih.gov/pubmed/16319173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0742
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