The Eukaryotic Elongation Factor 1A Is Critical for Genome Replication of the Paramyxovirus Respiratory Syncytial Virus

The eukaryotic translation factor eEF1A assists replication of many RNA viruses by various mechanisms. Here we show that down-regulation of eEF1A restricts the expression of viral genomic RNA and the release of infectious virus, demonstrating a biological requirement for eEF1A in the respiratory syn...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wei, Ting, Li, Dongsheng, Marcial, Daneth, Khan, Moshin, Lin, Min-Hsuan, Snape, Natale, Ghildyal, Reena, Harrich, David, Spann, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257679/
https://ncbi.nlm.nih.gov/pubmed/25479059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114447
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