The Eukaryotic Elongation Factor 1A Is Critical for Genome Replication of the Paramyxovirus Respiratory Syncytial Virus

The eukaryotic translation factor eEF1A assists replication of many RNA viruses by various mechanisms. Here we show that down-regulation of eEF1A restricts the expression of viral genomic RNA and the release of infectious virus, demonstrating a biological requirement for eEF1A in the respiratory syn...

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Udgivet i:PLoS One
Main Authors: Wei, Ting, Li, Dongsheng, Marcial, Daneth, Khan, Moshin, Lin, Min-Hsuan, Snape, Natale, Ghildyal, Reena, Harrich, David, Spann, Kirsten
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257679/
https://ncbi.nlm.nih.gov/pubmed/25479059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114447
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