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Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis

Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was found to participate in this process downstream of ER...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stoianov, Alexandra M., Robson, Debra L., Hetherington, Alexandra M., Sawyez, Cynthia G., Borradaile, Nica M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478042/
https://ncbi.nlm.nih.gov/pubmed/26102086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131269
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