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How does hepatic lipid accumulation lead to lipotoxicity in non-alcoholic fatty liver disease?

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), characterized as excess lipid accumulation in the liver which is not due to alcohol use, has emerged as one of the major health problems around the world. The dysregulated lipid metabolism creates a lipotoxic environment which promotes the devel...

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Detalhes bibliográficos
Publicado no:Hepatol Int
Main Authors: Geng, Yana, Faber, Klaas Nico, de Meijer, Vincent E., Blokzijl, Hans, Moshage, Han
Formato: Artigo
Idioma:Inglês
Publicado em: Springer India 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886759/
https://ncbi.nlm.nih.gov/pubmed/33548031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-020-10121-2
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