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DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity

Intracellular lipid accumulation in the heart is associated with cardiomyopathy, yet the precise role of triglyceride (TG) remains unclear. With exercise, wild type hearts develop physiologic hypertrophy. This was associated with greater TG stores and a marked induction of the TG-synthesizing enzyme...

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Detalhes bibliográficos
Main Authors: Liu, Li, Shi, XiaoJing, Bharadwaj, Kalyani G., Ikeda, Shota, Yamashita, Haruyo, Yagyu, Hiroaki, Schaffer, Jean E., Yu, Yi-Hao, Goldberg, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794747/
https://ncbi.nlm.nih.gov/pubmed/19778901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049817
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