Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

Hepatic steatosis is often associated with insulin resistance and obesity and can lead to steatohepatitis and cirrhosis. In this study, we have demonstrated that hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), two enzymes critical for lipolysis in adipose tissues, also contrib...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reid, Brendan N., Ables, Gene P., Otlivanchik, Oleg A., Schoiswohl, Gabriele, Zechner, Rudolf, Blaner, William S., Goldberg, Ira J., Schwabe, Robert F., Chua, Streamson C., Huang, Li-Shin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442319/
https://ncbi.nlm.nih.gov/pubmed/18337240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800533200
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