Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

Hepatic steatosis is often associated with insulin resistance and obesity and can lead to steatohepatitis and cirrhosis. In this study, we have demonstrated that hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), two enzymes critical for lipolysis in adipose tissues, also contrib...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Reid, Brendan N., Ables, Gene P., Otlivanchik, Oleg A., Schoiswohl, Gabriele, Zechner, Rudolf, Blaner, William S., Goldberg, Ira J., Schwabe, Robert F., Chua, Streamson C., Huang, Li-Shin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2008
Θέματα:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442319/
https://ncbi.nlm.nih.gov/pubmed/18337240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800533200
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