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Repeat Sequences in Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Targets of Antibodies Associated with Protection from Malaria

Human antibodies to the block 2 region of Plasmodium falciparum merozoite surface protein 1 (MSP1) are associated with a reduced prospective risk of clinical malaria. Block 2 is highly polymorphic, but all known alleles can be grouped into three major types. Two of these types (the K1-like and MAD20...

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Autors principals: Polley, Spencer D., Tetteh, Kevin K. A., Cavanagh, David R., Pearce, Richard J., Lloyd, Jennifer M., Bojang, Kalifa A., Okenu, Daniel M. N., Greenwood, Brian M., McBride, Jana S., Conway, David J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152097/
https://ncbi.nlm.nih.gov/pubmed/12654798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1833-1842.2003
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